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The combination of XL765 (30 mg/kg) with chloroquine (50 mg/kg) results in significant inhibition of BxPC-3 xenograft growth in mice models
DMSO : 150 mg/mL (358
27)28)32-20-8-7-16(13-22(20)35-2)33-9-11-36-12-10-33
943319-70-8
H2O : 25 mg/mL (65
CDK8-IN-1 4914 The combination of XL765 (30CDK8 IN 1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM. Product information CAS Number: 1629633 48 2 Molecular Weight: 255. 20 Formula: C11H8F3N3O Chemical Name: 4 (pyridin 4 yl) 3 (trifluoromethyl) 1H pyrrole 2 carboxamide Smiles: NC(=O)C1NC=C(C=1C(F)(F)F)C1C=CN=CC=1 InChiKey: RKTPHHQXNCHBCF UHFFFAOYSA N InChi: InChI=1S C11H8F3N3O c12 11(13,14)8 7(5 17 9(8)10(15)18)6 1 3 16 4 2 6 h1 5,17H,(H2,15,18) Technical Data Appearance: Solid
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